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Getting off proton pump inhibitors

I have a couple patients on it who I’d like to get off of Prilosec and was wondering what you recommend. Do they need to taper off of it? Can they take herbs for it while they are tapering off? What do you think of the patent wei ti ling to treat the acid reflux? I also have been treating a baby with digestion problems who is also on Prilosec with craniosacral. It is helping but was wondering if you had any more ideas for the babes. I’d like to get him off of it as well.

I was thinking about how I admire your practice so much and all the great work you do! As I continue to practice I realize how much work it is to get it all in; lab work, herbs, supplements, research, studying the classics, training, finances, business knowledge, marketing, etc. and you really do such a great job with it all!

– Santa Cruz Acupuncturist

Dear Santa Cruz Acupuncturist,

Thank you so much for all of the kind words.  They are appreciated!

Prilosec is tough.  I am sure you know the side effects of shutting off the stomach acid completely, as these proton pump inhibitors do.   Without some stomach acidity it is impossible to absorb iron or Vitamin B-12 and very difficult to absorb calcium.  Women are 2.4 times more likely to develop osteoporosis on PPI’s.  Without iron assimilation there can iron deficient or microcytic anemia.  Without B-12 you develop macrocytic anemia or eventually pernicious anemia which can be fatal.

Also, without stomach acidity we lose the first barrier against bacterial overgrowth and damage to the stomach and intestines.  We constantly ingest pathogenic bacteria and viruses’  The high acidity of the stomach kills most of them before they can take up residence in the intestines. The rate of C. Dificile infections, which is often a fatal gut infection, skyrockets in those on PPI’s.

So, it is a very nasty and 95% of the time unnecessary drug.

That said, it is very difficult, but not impossible, to get off of this class of drugs.  The rebound is usually worse than the original problem.  Great marketing eh?  give em a drug that they don’t need, that is very difficult to get off of and causes numerous known illnesses that require more pharmaceuticals.

The upper sphincter-like connection of the esophagus to the stomach is acid sensitive.  If there is acidity present in the stomach it closes more tightly so that the acid cannot get up into the esophagus.  Even weak stomach acid can erode the delicate tissues of the esophagus.  The body operates a lot on the “use it or lose it” principle.  If there is very low stomach acidity for more than a few weeks (Prilosec carries a warning not to take it for more than 14 days) the gastroesophageal junction gets lax.  Then, if you tray to get off of the prilosec, the sudden change in acidity, not held in place by the pseudo-sphincter, will allow easy reflux of food up into the esophagus.  This food even if only slightly acidic will burn the esoghagus.

Secondary to this is that the lower sphincter can also get lax.  The bile duct from the gallbladder empties into the duodenum of the small intestine just below this sphincter.  If the valve is lax the patient can be drawing and refluxing excess bile up through the valve into the stomach.  This is very, very caustic and can lead to GERD symptoms.  I see this a lot in endoscopies where the lower stomach has a large amount of bile in it.  This will cause the bitter, bile taste that we ask about in TCM.

If patients want off of the drug I urge them to talk to their MD, and wean off slowly.  The doctor will hopefully have them switch to an H2 agonist which is less overwhelming to the system and must be taken twice per day.  Then have them switch to a simple charcoal or calcium based antacid, and then to nothing.

It takes several weeks to months for the system to really function normally.  During this time I have patients follow a Taoist Food combining diet.  No mixing of foods that “fight with each other”.  Protein and starchy carbs should not be eaten together as they require different digestive enzymes to break them down, of different pH, that tend to neutralize each other.  When this happens, the weak stomach acid is not strong enough to digest the ingested food protein but is still strong enough to scorch the esophagus.

So, green vegetables are OK with either starches or proteins.  Fats OK with protein.  Fruit ALWAYS eaten separately from other foods except some lettuce or celery.  No dairy with meals.  Best to not to have dairy at all.

Eat the last meal as a very simple meal early in the evening as they will reflux when they lie down.
They will likely need to sleep with their upper body propped up until they return to normal.  Often a recliner is best for a month or more.

The original problem is almost always weak stomach acid.  The stomach acid is too weak to digest the food, so more weak stomach acid is pumped in until there is a large amount of very weak stomach acid and undigested food.  This refluxes and causes the GERD.  If the stomach acid is strengthened with herbs, hydrochloric acid supplements or eating citrus or vinegar (both acidic) with meals, the problem often disappears.  That is if you treeat it pre-prilosec.  During and immediately post prilosec you can’ do the acid or vinegar because of the lax sphincters.

I would also use probiotics to restore normal gut flora and enzymes to help assist the breakdown of food.

Many herbal possibilities are possible  depending on the TCM diagnoses.  Often there is liver depression qi stagnation assailing the stomach (and spleen) with stomach fire and rebellious stomach qi. In this case we need to include liver harmonizing herbs as well as spleen qi tonics and herbs to quell the fire and restrain the rebellious stomach qi.

If it is simple food stagnation, Bao He Wan or Curing pills may be enough.
Often in this condition, as I indicated above,  there is some gallbladder disharmony that might be addressed with a Wen Dan Tang formula derivative.
If there is conflicting cold/heat/ deficiency/excess issues, the old classic Ban Xia Xie Xin Tang or some of the related formulas can work magic.

In terms of the baby:  this is one of the most irritating things that I see in practice.  Given all the horrific problems in adults, how much worse to use this in a system that is not even close to being developed.  The Spleen/Stomach system is so often the source of disharmonies in children and to so disrupt them is horrific.  Babies are assimilation machines.  To limit assimilation is horrible.

Allergies, sensitivities, intestinal dysbiosis, and bad food combinations are usually at the source of dyspepsia in children and are usually very easily treated.

Introduce infant probiotics.  Jarrow makes a good probiotic for children caledl “Jarrow Babydophilus”.  For infants, I have mom put some on the nipple before/during breast feeding.

Colostrum from mothers pre-milk is loaded with immune factors to turn on the stomach.  If infants are denied this for any reason, or are given antibiotics, they will nearly always have problems.  I would use some goat milk colostrum applied to the nipple.

There many great children’s formulas available for this.  I carry children’s tinctures from K’an, Blue Poppy, and Bioessence.  Of the 27 children’s formulas that I carry as tinctures, 13 are for problems rooted in spleen/stomach/digestive issues.  Each of these companies has good support material for symptom/pattern/formula relationships.

Check around the anus of the baby.  If there is any inflammation, there is an allergenic problem and the food supply must be changed.  If any new foods are added, they should never be added more frequently than one new food per week.  The anus should be checked for irritation.  If there is any irritation, the food should be immediately removed.

Dr. John Nieters, L.Ac. DAOM

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Xiao Yao, popular women’s formula

Hello John,
I am currently experiencing sadness (from a break-up), more than actual anger (when I was in the relationship). I looked up the xiao yao formula and found some inexpensive stuff on the net. I got the name ‘jai wei xiao yao wan’ and found a formula called Free and Easy Wanderer Plus teapills by Plum Flower brand.  What do you think? Is this a brand you would recommend continuing with?  Thanks for any thoughts and opinions you can offer,

– Raven

Dear Raven,
Sorry to hear about the relationship issues, although I am very happy that you are not experiencing as much anger.  Anger deranges almost all body functions, including dramatic reduction in immune health. Dan Zhi Xiao Yao and Xiao Yao are the #1 and #2 selling formulae in the United States.   We are a country of frustration and unfulfilled desires, which causes liver depression qi stagnation (that then generally assails the spleen causing spleen deficiency) which these formulas treat.  Dan Zhi Xiao Yao San (sometimes called Jia Wei Xiao Yao San) is stronger to treat the depressive heat build up which can lead to  symptoms such as anger, frustration, acne, headache, etc.

I like to start women out with generic types of formulas for exactly this reason;  if they work they are easy to find.  I like to fine tune them to more specifically to address the individual.

Mayway/ Plum flower is a very good company.  That being said, teapills are very weak.  The company that I use for these formulae has a dramatically higher extraction ratio, so it takes less to do the job.  You would need about a half bottle of teapills per day to equal the dosing of the versions that I carry.

– Dr. John Nieters, L.Ac. DAOM, FABORM

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Back pain during pregnancy

“I started going to John for my back pain about 2 months ago, and with first appointment, it significantly improved and after like 2 or 3rd appt, the pain was completely gone.  His approach is very comprehensive and I feel very comfortable with John, who is warm and very kind.   I am about 5 months pregnant now, but he knows how to treat pregnant woman, so there is no need to worry about.  Every time I go to the appointment, I feel so much better, and I highly recommend him for anyone who has health issues.”

Posted by MN on Yelp 5/24/11

Thank you MN for sharing your experience. I am so glad that you had relief from your pain. I am going to do a special episode of The Balancing Point radio show, explaining why acupuncture works for pain on Monday 5/30/11 from 9-10am. If you want to know more, please tune-in on the radio KEST 1450 AM or listen to the podcast which will be available at www.thebalancingpoint.net, after the show.

– Dr. John Nieters, L.Ac. DAOM, FABORM

Read the follow up to this post on John’s women’s health and fertility blog: www.alamedafertility.com

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Considering Artificial Insemination

Hi John,
Koichi gave me your name. I’ve been under his care for four years. I would like to ask your advice about something.

I am in Israel right now, beginning the process of having a child by artificial insemination. I am almost 40. There are expert doctors here, and the process is very common, but they also pump you full of hormones, which scares me as much as anything. I am a staunch advocate of holistic health, and have been preparing my body for this for years (nutrition, exercise, saunas, Network, cleanse). I intend to do acupuncture too. Can you give me some advice about whether I should try IUI or IFV, with or without hormones? I need the perspective of someone who understands holistic medicine. I feel like it’s a race against time. Someone also pointed out that the time has passed for it to be a natural process anyway. Maybe it’s worth the discomfort in this case. If you have any advice or someone I could talk to I would really appreciate it.

Thank you,

– A.I. in Israel

Dear A.I. in Israel,
Happy to point you in a direction or give you some information myself.

I would need to know a bit more information to be able to assist you.  The choice between IUI and IVF would be dependent on the answers to some of the following questions.  Also, the hormone questions would be better answered with more information.  Answer what you are comfortable with.

Reason for artificial insemination?
Have you been pregnant before?
Other fertility methods attempted; including sex?
Have you ever been given Clomid or other fertility drugs?
Any history of diabetes, polycystic ovaries, endometriosis, or uterine myomas (fibroids)?
Have you been or will you be doing herbal treatments?
Have you had an ultrasound or hysterosalpingogram to visualize the uterus and fallopian tubes?
Are you doing a Basal Body Temperature chart of your menstrual cycle.
Hormone levels now.  Have you had:
Thyroid – TSH, T3, reverse T3
female hormones – FSH, LH, progesterone, primarily
Vitamin D level
Inflammatory markers – C-reactive protein, homocysteine
antibodies/autoimmune – Lupus, anti-cardiolipin, or any others

I look forward to addressing the considerations involved.

– Dr. John Nieters, L.Ac. DAOM, FABORM

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Cholesterol, MD says normal

Dear John,
I just receive my cholesterol panel and vitamin D results from my MD, he says my test is normal. Total cholesterol 132. HDL 45, LDL 71, triglycerides at 78. Vitamin D is 84. My understanding was that the blood calcium level was going to be checked.  With a Vitamin D level of 84, is there a risk that I am taking too much calcium?  My MD seemed to think that I would have to have major health issues before calcium deposits would form.  Do I need to have this done?
– Over 40 Mom

Dear Over 40 Mom,

I think that your total cholesterol and HDL are too low.  Cholesterol is the precursor for most of your hormones.  Low levels (which you have) are associated with higher rates of many illnesses and many psychological issues.  The best way to increase cholesterol levels is through increased moderate stress exercise and increasing fish or krill oil intake.  For women I like to see HDL levels over 70.

High cholesterol in women is almost (the exception being in some diabetic women and familial high cholesterol in the 700-800 range) a non factor for heart disease and stroke.  Low cholesterol is the problem for women.  I have two meta analysis with a total of 44 cholesterol studies looked at that show this.

With you vitamin D level I would personally recommend against added calcium supplementation.  There are conflicting studies in this area of calcium supplementation. There are good studies showing problems with calcium supplementation along with normal to high Vitamin D levels.  Eat a good diet and you should be getting enough calcium.

– Dr. John Nieters, L.Ac. DAOM, FABORM

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